Author: biotheryx

Study to Evaluate the Safety, Pharmacokinetics and Preliminary Efficacy of BTX-1188 in Patients with Advanced Hematologic and Solid Tumor Malignancies

SAN DIEGO, Jan. 26, 2022 — BioTheryX, Inc., a clinical-stage company focused on developing targeted protein degraders to create life-saving medicines, today announced dosing of the first patient in a new, first-in human Phase 1 study investigating its lead candidate BTX-1188, an oral, dual target protein degrader specifically engineered to degrade GSPT1 and IKZF1/3, in patients with advanced hematologic and solid tumor malignancies.

“BTX-1188 has demonstrated rapid, deep and durable degradation of both GSPT1 and IKZF1/3 at low nanomolar concentrations in preclinical models, and we are delighted to make this exciting advancement into the clinic,” said Zung Thai, M.D., Ph.D., Chief Medical Officer of BioTheryX. “We are grateful to our clinical trial site partners for initiating this study in these challenging times and thank them for their commitment to investigating potential new therapeutic options for people facing difficult-to-treat cancers.”

The Phase 1 clinical trial is a multicenter, open label, non-randomized, sequential dose escalation study to assess the safety, pharmacokinetics and preliminary efficacy of BTX-1188 in patients with acute myeloid leukemia, advanced lymphoid and solid tumors who have failed standard therapy. The primary objective of the Phase 1 study is to determine a recommended Phase 2 dose, which will then be carried forward into expansion cohorts where the safety and efficacy of BTX-1188 will be evaluated in both hematologic and solid tumor malignancies. More information can be found on clinicaltrials.gov (NCT05144334).

“BTX-1188 is one of many potential best-in-class protein degrader candidates our team has designed and developed leveraging our distinctive PRODEGY targeted protein degradation platform to provide new treatment approaches for people living with cancer and other diseases,” said Philippe Drouet, President and Chief Executive Officer of BioTheryX. “With our clinical trial site partners, we are working as expeditiously as possible to study BTX-1188 and validate the potential of our platform.”

About BTX-1188

BTX-1188 is the first orally bioavailable, rationally designed dual target protein degrader, engineered to specifically degrade validated oncology targets GSPT1 and IKZF1/3. By degrading GSPT1 and IKZF1/3, BTX-1188’s profile is expected to be differentiated from protein degraders that exclusively target GSPT1. Preclinical data for BTX-1188 has shown rapid, deep and durable degradation of these targets at low nanomolar concentrations. Acute myeloid leukemia (AML) xenograft experiments have also shown significant decreases in tumor volume and increased survival compared to controls and other degraders of GSPT1. BioTheryX believes BTX-1188 has broad potential applicability in both hematologic and solid tumor malignancies and is currently studying the molecule in both settings as part of a Phase 1 clinical study.

About BioTheryX, Inc.

BioTheryX is a clinical-stage biopharmaceutical company dedicated to improving the lives of patients suffering from cancer, inflammatory and immunological diseases through the discovery, development and commercialization of targeted protein degradation therapies. We leverage our proprietary PRODEGY technology platform and differentiated targeted protein degradation approach to design small molecules that regulate protein homeostasis. We believe our approach is applicable to a broad range of diseases and has the potential to target proteins that have historically been considered undruggable. Our initial programs are focused on oncology indications with high unmet medical need. For more information, please visit www.biotheryx.com and engage with us on LinkedIn.

Contacts:

Investors/Media
212.600.1902
[email protected]

SAN DIEGO, Jan. 20, 2022 — BioTheryX, Inc., a clinical-stage company focused on targeted protein degradation to create life-saving medicines, today announced the appointment of Sahm Nasseri as Chief Business Officer.

“Sahm is an accomplished biopharma leader with impressive experience in business development, corporate strategy, commercialization and program management. His expertise and leadership, most recently growing the U.S operations of an international biotech company and previously leading global commercial franchises for Merck, will help advance our pipeline of best-in-class protein degraders,” said Philippe Drouet, President and Chief Executive Officer of BioTheryX. “As the company’s first Chief Business Officer, Sahm will play an important role in establishing relationships with potential collaborators as we continue to expand our research and development programs.”

Mr. Nasseri previously served as Chief Executive Officer of PYC Therapeutics, an RNA therapeutics company based in the United States and Australia, where he built out the Company’s U.S. presence and preclinical, clinical and corporate development teams. Prior to this, Mr. Nasseri served at Merck & Co for seven years as a leader across business development, investor relations and corporate strategy functions where he gained extensive commercial drug development experience. He led global strategy for Merck’s growing oncology organization and served as interim Vice President and Global Product Leader for Merck’s HPV Vaccines, a family of vaccines with over $4 billion in annual revenue. Before Merck, Mr. Nasseri worked as a strategy consultant for McKinsey & Company. Mr. Nasseri holds a Bachelor of Chemical Engineering from the University of New South Wales in Sydney and an MBA from Columbia Business School in New York City.

“The outstanding team at BioTheryX has spent years building the leading targeted protein degradation platform in the industry. This PRODEGY platform is now poised to make a significant impact on patients with cancer with the lead protein degrader program entering Phase 1 clinical trials,” said Mr. Nasseri. “I am passionate about bridging great science towards the efficient development of medicines that can address important unmet patient needs and as such, I am excited to join BioTheryX and support the ongoing growth of the company and the continued development of its pipeline of first-in-class and best-in-class protein degradation therapies.”

About BioTheryX, Inc.

BioTheryX is a clinical-stage biopharmaceutical company dedicated to improving the lives of patients suffering from cancer, inflammatory and immunological diseases through the discovery, development and commercialization of targeted protein degradation therapies. We leverage our proprietary PRODEGY technology platform and differentiated targeted protein degradation approach to design small molecules that regulate protein homeostasis. We believe our approach is applicable to a broad range of diseases and has the ability to address protein targets that have historically been considered undruggable. Our initial programs are focused on oncology indications with high unmet medical need. For more information, please visit www.biotheryx.com and engage with us on LinkedIn.

Contacts:

Investors/Media
[email protected]

Enrollment for Phase 1 Clinical Trial to Commence by End of 2021

SAN DIEGO, Nov. 2, 2021 /PRNewswire/ —

BioTheryX, Inc., a clinical-stage company focused on targeted protein degradation to create life-saving medicines, today announced that the U.S. Food and Drug Administration (FDA) cleared the company to proceed with a Phase 1 clinical trial of BTX-1188 in hematologic and solid malignancies.

BTX-1188 is a novel oral small molecule cereblon binder that has immunomodulatory properties and promotes the degradation of a neosubstrate G1 to S phase transition 1 (GSPT1), a translation termination factor, as well as IKZF1/3, zinc finger transcription factors important in hematological function. By degrading multiple proteins including GSPT1 and IKZF1/3, BTX-1188’s profile is expected to be differentiated from protein degraders that exclusively target GSPT1. BTX-1188 has demonstrated promising preclinical activity against a variety of leukemias and solid tumors.

“The FDA clearance to begin our Phase 1 study for BTX-1188 is a major milestone for BioTheryX, which represents our first molecular glue to enter clinical development, and the second IND clearance for our pipeline,” said Zung Thai, M.D., Ph.D., Chief Medical Officer of BioTheryX. “We plan to study BTX-1188 in patients with hematological and solid malignancies who have limited treatment options and for whom new therapies are desperately needed. We expect to initiate patient enrollment in the Phase I study by year end.”

The Phase I clinical trial is designed to assess the safety and tolerability of BTX-1188 and to determine the recommended Phase 2 dose. Following determination of the recommended Phase 2 dose, the company plans to further evaluate the safety and efficacy of BTX-1188 in expansion cohorts in both hematological and solid tumor malignancies.

About BioTheryX, Inc.

BioTheryX is a clinical-stage biopharmaceutical company focused on restoring protein homeostasis, including protein degradation and modulation, and multi-kinase inhibition to develop treatments intended to extend and improve the quality-of-life of patients with cancer and other diseases. Our principal technology platform centers on targeted protein degradation, ‘molecular glues’ and Proteolysis Targeting Chimeras, that enable the design of small molecules to regulate protein equilibrium. This technology is designed to utilize the body’s own protein disposal system to selectively degrade and remove disease-causing proteins. It has potential applicability for a broad range of diseases, including targets that have to date been considered ‘undruggable’, and BioTheryX is initially focused on treating oncology indications with high unmet need.  For more information, please visit www.biotheryx.com and engage with us on LinkedIn.

Contact

Media and Investor Contact:
Amy Conrad, Juniper Point
(858) 366-3243
[email protected]

SAN DIEGO, Oct. 28, 2021 /PRNewswire/ —

BioTheryX, Inc., a clinical-stage company focused on targeted protein degradation to create life-saving medicines, today announced the appointment of Philippe Drouet as President and Chief Executive Officer of BioTheryX.

“Philippe is an extremely talented biopharma executive with more than two decades of global experience in commercializing blockbuster oncology therapeutics. He has worked to advance products through clinical development, successfully launched them, and most importantly made them available to patients. His proven track record in building effective high performing teams will position us well to advance our pipeline of protein degraders and modulators to create life-saving medicines for patients,” said David Stirling, Ph.D., Executive Chairman of BioTheryX. “The Board and I welcome him as CEO, and we are excited to have him lead our company as we build on our expertise in protein modulation-based drug development.”

Prior to joining BioTheryX, Mr. Drouet served as Chief Commercial Officer at CRISPR Therapeutics where he shaped the strategy for the launch of the company’s first allogeneic CAR-T therapies and helped lead the clinical development strategy for the company’s phase I clinical assets. Previously, Philippe served as Senior Vice President, Global Oncology at Merck & Co. where he launched and commercialized Keytruda®, drove substantial global oncology revenue and built and led the company’s Global Oncology Marketing, Access and Pricing organization.  Prior to that, he served as President of Hospira’s U.S. division before Hospira’s acquisition by Pfizer in 2015. Philippe also held roles of increasing responsibility at Novartis Pharmaceutical Corporation, including Vice President U.S. Hematology, General Manager Oncology in Turkey, Global Brand Leader for Gleevec® and Head of Oncology Marketing in Canada. Philippe received an MBA from INSEAD in France and a Master of Science and Bachelor in Chemical Engineering from McGill University, Canada.

“I am excited to join BioTheryX and lead the company through its next stage of rapid growth as it expands its programs in the fast-paced category of protein degradation,” said Mr. Drouet. “BioTheryX has built one of the leading scientific teams and most promising pipelines in the protein degradation space. I look forward to working alongside this outstanding team to build our clinical-stage program for liquid and solid tumors and develop first-in-class therapies in areas of high unmet medical need in oncology and other diseases.”

About BioTheryX, Inc.

BioTheryX is a clinical-stage biopharmaceutical company dedicated to improving the lives of patients suffering from cancer and inflammatory and immunological diseases through the discovery, development and commercialization of therapies that restore protein homeostasis through targeted protein degradation and modulation, and multi-kinase inhibition. We leverage our proprietary Protein Homeostatic Modulator technology platform and differentiated targeted protein degradation approach to design small molecules that regulate protein homeostasis. We believe our approach is applicable to a broad range of diseases, in particular those driven by protein targets that have been considered undruggable. Our initial programs are focused on oncology indications with high unmet medical need. For more information, please visit www.biotheryx.com and engage with us on LinkedIn.

Contact

Media and Investor Contact:
Amy Conrad, Juniper Point
(858) 366-3243
[email protected]

SAN DIEGO, Aug. 6, 2021 /PRNewswire/ —

BioTheryX, Inc., a clinical-stage company focused on creating life-saving medicines through targeted protein degradation, today announced the appointments of Nancy Miller-Rich, John A. Hohneker, M.D., and Diantha Duvall to its Board of Directors.

“The wealth of biotech leadership and industry knowledge that Nancy, John, and Diantha bring to our board will be invaluable as we advance our pipeline and execute on our strategic goals,” said David Stirling, Ph.D., President and CEO of BioTheryX.  “Nancy is a veteran life sciences executive and board member with significant expertise in corporate and commercial strategy.  John brings extensive drug development experience to BioTheryX and has been instrumental in the approval and commercialization of seven drugs across multiple therapeutic categories.  Diantha is a well-respected public company executive with experience across a broad range of financial and business disciplines that underpin biotech and large pharmaceutical company operations.  We look forward to Nancy, John, and Diantha’s guidance as we aim to build a leading protein degradation company.”

Appointee Bios:

Nancy Miller-Rich has 35 years of experience in the healthcare industry, with significant expertise in business development and commercial strategy. Since September 2017, Ms. Miller-Rich has served as a consultant to the pharmaceutical industry. Previously, Ms. Miller-Rich served in a number of leadership roles at Merck & Co., Inc. and, prior to the merger of the two companies, at Schering-Plough Corporation, including most recently as Senior Vice President, Global Human Health Business Development & Licensing, Strategy and Commercial Support and as Group Vice President, Consumer Care Global New Ventures and Strategic Commercial Development. Prior to joining Schering-Plough, Ms. Miller-Rich served in a variety of commercial and marketing roles at Sandoz Pharmaceuticals and Sterling Drug, Inc. She is currently a director of Aldeyra Therapeutics, Inc., Intercept Pharmaceuticals, Kadmon Holdings, Inc., and 4D Molecular Therapeutics, Inc., as well as a board member of a number of private and not-for-profit entities. She received her B.S. in Business Administration, Marketing from Ithaca College in Ithaca, New York.

John A. Hohneker, M.D. brings over 30 years of drug development and leadership experience within the biotech and pharmaceutical industry to the BioTheryX board.  He has served in several key leadership roles including as President and CEO of Anokion SA and President of Research and Development at FORMA Therapeutics Inc., where he guided the Company’s transition from a discovery-stage biotech to one with multiple programs in clinical trials.  He also held several roles at Novartis AG, most recently as Senior Vice President and Global Head of Development for Immunology and Dermatology, where he led the development and registration of Cosentyx® and Ilaris®.  During his tenure at Novartis, Dr. Hohneker also played a key role in the development, approval, and commercialization of several products including Gleevec®, Tasigna®, Zometa®, Afinitor® and Exjade®.  Prior to joining Novartis, he held positions of increasing responsibility at Glaxo Wellcome and its legacy company, Burroughs Wellcome. He received an MD from the University of Medicine and Dentistry of New Jersey at Rutgers Medical School.  Dr. Hohneker completed his internship and residency in Internal Medicine and his fellowship in Medical Oncology at the University of North Carolina Hospitals.

Diantha Duvall is an experienced financial and business leader in the life sciences sector who currently serves as Chief Financial Officer of Genocea, a leading cancer immunotherapy company.  Prior to joining Genocea in 2019, Ms. Duvall held several positions of increasing responsibility including Vice President, Controller and Chief Accounting Officer at Bioverativ, Inc., U.S. and Global Commercial Controller at Biogen, and Executive Director at Merck and Co.  While at Merck, her experiences spanned roles in venture investment, business development, joint ventures, and alliances, as well as operational controls and technical accounting.  In addition, she gained extensive experience in SEC reporting, Sarbanes Oxley compliance, transaction support and risk management while at PricewaterhouseCoopers.  Ms. Duvall received a bachelor’s degree in Economics and Public Policy from Colby College and masters’ degrees in both Accounting and Business Administration from Northeastern University. Ms. Duvall is a Certified Public Accountant licensed in the state of Massachusetts.

About BioTheryX, Inc.

BioTheryX is a clinical-stage biopharmaceutical company dedicated to improving the lives of patients suffering from cancer and inflammatory and immunological diseases through the discovery, development and commercialization of therapies that restore protein homeostasis through targeted protein degradation and modulation, and multi-kinase inhibition. We leverage our proprietary Protein Homeostatic Modulator technology platform and differentiated targeted protein degradation approach to design small molecules that regulate protein homeostasis. We believe our approach is applicable to a broad range of diseases, in particular those driven by protein targets that have been considered undruggable. Our initial programs are focused on oncology indications with high unmet medical need.  For more information, please visit www.biotheryx.com and engage with us on LinkedIn.

Contact

Media and Investor Contact:
Amy Conrad, Juniper Point
(858) 366-3243
[email protected]

SAN DIEGO, June 9, 2021 /PRNewswire/ —

BioTheryX, Inc., a clinical-stage company focused on degrading proteins to create life-saving medicines, today announced the dosing of the first patient in a dose escalation clinical trial of BTX-A51 in advanced solid tumor malignancies that are dependent upon MYC, one of the most commonly known oncogenic drivers. BTX-A51, the company’s lead multi-kinase inhibitor is also currently in a phase 1 dose escalation clinical trial for advanced hematological malignancies.

“This is a significant milestone for BioTheryX, as we look to deliver a much-needed therapeutic option to patients with advanced solid tumor malignancies that are dependent upon MYC,” said Robert Williamson, President and CEO of BioTheryX.  “We are excited for the potential of BTX-A51 to provide a meaningful therapeutic option for patients and are working aggressively to advance our pipeline of molecular glues, Proteolysis Targeting Chimeras and monovalent degraders towards the clinic.”

BTX-A51 is an oral small molecule, multi-kinase inhibitor designed to block a specific leukemic stem cell target (CK1α) as well as super enhancer targets (CDK7/CDK9) preventing transcription of key oncogenic genes. This therapeutic mechanism entails activation of p53, an important tumor suppressor, and its sustained stabilization by super-enhancer shutdown of MDM2, a protein degrader of p53, in combination with transcriptional shutdown of leukemia oncogenes, such as MYC and MCL-1.  Blocking CKIα, CDK7, and CDK9 augments and synergistically stabilizes p53 and downregulates MYC and MCL-1 promoting the rapid killing of leukemia cells as well as leukemic stem cells. Pre-clinical results have been published in a peer-reviewed Cell article, demonstrating BTX-A51’s favorable efficacy in animals.

“In the fight against solid tumor cancers, which have extremely poor survival rates and limited treatment options, clinical trials with new therapies are desperately needed,” added Zung Thai, M.D., Ph.D., Chief Medical Officer of BioTheryX.  “We are excited to be initiating the dose escalation portion of this study and progressing to the selection of the Phase 2 dose.”

BioTheryX’s Phase 1 clinical trial of BTX-A51 is currently ongoing and recruiting patients.   The clinical trial is designed to assess the safety and tolerability of BTX-A51 and to determine the recommended Phase 2 dose.  Following determination of the recommended Phase 2 dose, we plan to further evaluate the safety and efficacy of BTX-A51 in expansion cohorts in both hematological and solid tumor malignancies.

About BioTheryX, Inc.

BioTheryX is a clinical-stage biopharmaceutical company focused on restoring protein homeostasis, including protein degradation and modulation, and multi-kinase inhibition to develop treatments intended to extend and improve the quality-of-life of patients with cancer and other diseases. Our principal technology platform centers on targeted protein degradation, PHM® ‘molecular glues’, that enable the design of small molecules to regulate protein equilibrium. This technology is designed to utilize the body’s own protein disposal system to selectively degrade and remove disease-causing proteins. It has potential applicability for a broad range of diseases, including targets that have to date been considered ‘undruggable’, and BioTheryX is initially focused on treating oncology indications with high unmet need.  For more information, please visit www.biotheryx.com and engage with us on LinkedIn.

Contact

Media and Investor Contact:
Amy Conrad, Juniper Point
(858) 366-3243
[email protected]

SAN DIEGO, May 25, 2021 /PRNewswire/ —

BioTheryX, Inc., a clinical-stage company focused on degrading proteins to create life-saving medicines, today announced that the company will present virtually at the 2021 Jefferies Virtual Healthcare Conference on Tuesday, June 1st, 2021 at 1:30 pm ET.   A live webcast of the presentation can be accessed here and will be made available on the company’s website under the Events section.

Robert Williamson, President and CEO, will present an overview on the company’s targeted protein degradation platform, its clinical stage oncology pipeline, and the management team will participate with him in 1x1s with investors.

About BioTheryX, Inc.

BioTheryX is a clinical-stage biopharmaceutical company focused on restoring protein homeostasis, including protein degradation and modulation, and multi-kinase inhibition to develop treatments intended to extend and improve the quality-of-life of patients with cancer and other diseases. Our principal technology platform centers on targeted protein degradation, PHM® ‘molecular glues’, that enable the design of small molecules to regulate protein equilibrium. This technology is designed to utilize the body’s own protein disposal system to selectively degrade and remove disease-causing proteins. It has potential applicability for a broad range of diseases, including targets that have to date been considered ‘undruggable’, and BioTheryX is initially focused on treating oncology indications with high unmet need.  For more information, please visit www.biotheryx.com and engage with us on LinkedIn.

Contact

Media and Investor Contact:
Amy Conrad, Juniper Point
(858) 366-3243
[email protected]

SAN DIEGO, May 20, 2021 /PRNewswire/ —

BioTheryX, Inc., a clinical-stage company focused on degrading proteins to create life-saving cancer medicines, today announced a $92 million Series E financing led by Farallon Capital Management, with participation from additional new investors Avidity Partners, Deep Track Capital, Irving Investors, Janus Henderson Investors, Lumira Ventures, Point72, Rock Springs Capital, Surveyor Capital, Tekla Capital Management, Alexandria Venture Investors and Wedbush Healthcare Partners, and existing investors.

The proceeds from the financing will be used to advance multiple molecular glues, PHM-based Proteolysis Targeting Chimeras and monovalent degraders, including BTX-1188, toward clinical development.  BioTheryX also plans to advance the clinical development of its lead multi-kinase inhibitor, BTX-A51, for the treatment of acute myeloid leukemia, myelodysplastic syndromes and solid tumors.

“We are pleased to have the support of an elite group of investors who share BioTheryX’s vision of realizing the promise of targeted protein degradation and delivering benefit to patients,” said Robert Williamson, President and CEO of BioTheryX.  “With this financing, we are well positioned to execute our plans to bring our first molecular glue program BTX-1188 into the clinic by the end of 2021, expand our platform of molecular glues, Proteolysis Targeting Chimeras and monovalent degraders and progress our lead program BTX-A51 through Phase 1.”

About BioTheryX, Inc.

BioTheryX is a clinical-stage biopharmaceutical company focused on restoring protein homeostasis, including protein degradation and modulation, and multi-kinase inhibition to develop treatments intended to extend and improve the quality-of-life of patients with cancer and other diseases. Our principal technology platform centers on targeted protein degradation, PHM® ‘molecular glues’, that enable the design of small molecules to regulate protein equilibrium. This technology is designed to utilize the body’s own protein disposal system to selectively degrade and remove disease-causing proteins. It has potential applicability for a broad range of diseases, including targets that have to date been considered ‘undruggable’, and BioTheryX is initially focused on treating oncology indications with high unmet need.  For more information, please visit www.biotheryx.com and engage with us on LinkedIn.

Contact

Media and Investor Contact:
Amy Conrad, Juniper Point
(858) 366-3243
[email protected]

SAN DIEGO, May 18, 2021 /PRNewswire/ —

BioTheryX, Inc., a clinical-stage company focused on degrading proteins to create life-saving medicines, today announced the expansion of its Scientific Advisory Board (SAB) with the appointment of Brenda Schulman, Ph.D., Director of the Department of Molecular Machines and Signaling at Max Planck Institute of Biochemistry, Honorary Professor at Technical University of Munich, and adjunct faculty at St. Jude Children’s Research Hospital.

“Brenda is a highly decorated biochemist and a recognized key opinion leader in the field of protein degradation and ubiquitin biology. We are excited to welcome her to our SAB,” said Robert Williamson, President and CEO of BioTheryX. “She will be an invaluable resource to the BioTheryX SAB and scientific team, advising on our research platform and pipeline, and we are eager to benefit from her expertise.”

Dr. Schulman received her Ph.D. from MIT studying protein folding with Peter Kim before developing an interest in the regulation of protein degradation during her postdoctoral studies first at MGH Cancer Center with Ed Harlow, and then at Memorial Sloan-Kettering Cancer Center with Nikola Pavletich. Dr. Schulman’s research group studies biochemical mechanisms underlying regulation by ubiquitin and autophagy pathways. Her lab has developed methods and tools to probe fleeting intermediates in ubiquitin and ubiquitin-like protein transfer cascades, and implemented them to determine the structural mechanisms of major families of E3 ligases, with a particular focus on dynamic multiprotein complexes including cullin-RING E3 ligases. Dr. Schulman is an elected member of American Academy of Arts and Sciences, the National Academy of Sciences, EMBO, and the German National Academy Leopoldina, and has been recognized by awards including most recently the Gottfried Wilhelm Leibniz Prize and Ernst Jung Prize for Medicine.

“I’m thrilled to be joining the accomplished team at BioTheryX by serving on the company’s SAB,” commented Dr. Schulman. “BioTheryX’s compelling and competitive platform creates a wealth of potential applications to degrade proteins with molecular glues, PHM based Proteolysis Targeting Chimeras, and monovalent degraders. I look forward to leveraging my expertise in this area and helping to advance BioTheryX to its next stages of growth.”

The backgrounds of the entire BioTheryX SAB can be found on the leadership page of the company’s website at https://biotheryx1.wpengine.com/about-us/#leadership.

About BioTheryX, Inc.

BioTheryX is a clinical-stage biopharmaceutical company focused on restoring protein homeostasis, including protein degradation and modulation, and multi-kinase inhibition to develop treatments intended to extend and improve the quality-of-life of patients with cancer and other diseases. Our principal technology platform centers on targeted protein degradation, PHM^® ‘molecular glues’, that enable the design of small molecules to regulate protein equilibrium. This technology is designed to utilize the body’s own protein disposal system to selectively degrade and remove disease-causing proteins. It has potential applicability for a broad range of diseases, including targets that have to date been considered ‘undruggable’, and BioTheryX is initially focused on treating oncology indications with high unmet need. For more information, please visit www.biotheryx.com and engage with us on LinkedIn.

Contact

Media and Investor Contact:
Amy Conrad, Juniper Point
(858) 366-3243
[email protected]