A Powerful Drug Discovery Engine
Our principal technology platform centers on targeted protein degradation with our PHM® ‘molecular glues’, that enable the design of small molecules to regulate protein equilibrium. Molecular glues can be used to either create a complex of proteins that is more stable by attaching them, giving them better functionality by gluing a diseased protein to a “regulator” protein. This technology utilizes the body’s own protein disposal system to selectively degrade and remove disease-causing proteins. We believe our technology has the potential to address a broad range of disease targets, including those that have to date been considered undruggable.