Month: May 2021

Last Updated on September 29, 2022 by biotheryx

SAN DIEGO, May 25, 2021 /PRNewswire/ —

BioTheryX, Inc., a clinical-stage company focused on degrading proteins to create life-saving medicines, today announced that the company will present virtually at the 2021 Jefferies Virtual Healthcare Conference on Tuesday, June 1st, 2021 at 1:30 pm ET.   A live webcast of the presentation can be accessed here and will be made available on the company’s website under the Events section.

Robert Williamson, President and CEO, will present an overview on the company’s targeted protein degradation platform, its clinical stage oncology pipeline, and the management team will participate with him in 1x1s with investors.

About BioTheryX, Inc.

BioTheryX is a clinical-stage biopharmaceutical company focused on restoring protein homeostasis, including protein degradation and modulation, and multi-kinase inhibition to develop treatments intended to extend and improve the quality-of-life of patients with cancer and other diseases. Our principal technology platform centers on targeted protein degradation, PHM® ‘molecular glues’, that enable the design of small molecules to regulate protein equilibrium. This technology is designed to utilize the body’s own protein disposal system to selectively degrade and remove disease-causing proteins. It has potential applicability for a broad range of diseases, including targets that have to date been considered ‘undruggable’, and BioTheryX is initially focused on treating oncology indications with high unmet need.  For more information, please visit www.biotheryx.com and engage with us on LinkedIn.

Contact

Media and Investor Contact:
Amy Conrad, Juniper Point
(858) 366-3243
[email protected]

Last Updated on September 29, 2022 by biotheryx

SAN DIEGO, May 20, 2021 /PRNewswire/ —

BioTheryX, Inc., a clinical-stage company focused on degrading proteins to create life-saving cancer medicines, today announced a $92 million Series E financing led by Farallon Capital Management, with participation from additional new investors Avidity Partners, Deep Track Capital, Irving Investors, Janus Henderson Investors, Lumira Ventures, Point72, Rock Springs Capital, Surveyor Capital, Tekla Capital Management, Alexandria Venture Investors and Wedbush Healthcare Partners, and existing investors.

The proceeds from the financing will be used to advance multiple molecular glues, PHM-based Proteolysis Targeting Chimeras and monovalent degraders, including BTX-1188, toward clinical development.  BioTheryX also plans to advance the clinical development of its lead multi-kinase inhibitor, BTX-A51, for the treatment of acute myeloid leukemia, myelodysplastic syndromes and solid tumors.

“We are pleased to have the support of an elite group of investors who share BioTheryX’s vision of realizing the promise of targeted protein degradation and delivering benefit to patients,” said Robert Williamson, President and CEO of BioTheryX.  “With this financing, we are well positioned to execute our plans to bring our first molecular glue program BTX-1188 into the clinic by the end of 2021, expand our platform of molecular glues, Proteolysis Targeting Chimeras and monovalent degraders and progress our lead program BTX-A51 through Phase 1.”

About BioTheryX, Inc.

BioTheryX is a clinical-stage biopharmaceutical company focused on restoring protein homeostasis, including protein degradation and modulation, and multi-kinase inhibition to develop treatments intended to extend and improve the quality-of-life of patients with cancer and other diseases. Our principal technology platform centers on targeted protein degradation, PHM® ‘molecular glues’, that enable the design of small molecules to regulate protein equilibrium. This technology is designed to utilize the body’s own protein disposal system to selectively degrade and remove disease-causing proteins. It has potential applicability for a broad range of diseases, including targets that have to date been considered ‘undruggable’, and BioTheryX is initially focused on treating oncology indications with high unmet need.  For more information, please visit www.biotheryx.com and engage with us on LinkedIn.

Contact

Media and Investor Contact:
Amy Conrad, Juniper Point
(858) 366-3243
[email protected]

Last Updated on September 29, 2022 by biotheryx

SAN DIEGO, May 18, 2021 /PRNewswire/ —

BioTheryX, Inc., a clinical-stage company focused on degrading proteins to create life-saving medicines, today announced the expansion of its Scientific Advisory Board (SAB) with the appointment of Brenda Schulman, Ph.D., Director of the Department of Molecular Machines and Signaling at Max Planck Institute of Biochemistry, Honorary Professor at Technical University of Munich, and adjunct faculty at St. Jude Children’s Research Hospital.

“Brenda is a highly decorated biochemist and a recognized key opinion leader in the field of protein degradation and ubiquitin biology. We are excited to welcome her to our SAB,” said Robert Williamson, President and CEO of BioTheryX. “She will be an invaluable resource to the BioTheryX SAB and scientific team, advising on our research platform and pipeline, and we are eager to benefit from her expertise.”

Dr. Schulman received her Ph.D. from MIT studying protein folding with Peter Kim before developing an interest in the regulation of protein degradation during her postdoctoral studies first at MGH Cancer Center with Ed Harlow, and then at Memorial Sloan-Kettering Cancer Center with Nikola Pavletich. Dr. Schulman’s research group studies biochemical mechanisms underlying regulation by ubiquitin and autophagy pathways. Her lab has developed methods and tools to probe fleeting intermediates in ubiquitin and ubiquitin-like protein transfer cascades, and implemented them to determine the structural mechanisms of major families of E3 ligases, with a particular focus on dynamic multiprotein complexes including cullin-RING E3 ligases. Dr. Schulman is an elected member of American Academy of Arts and Sciences, the National Academy of Sciences, EMBO, and the German National Academy Leopoldina, and has been recognized by awards including most recently the Gottfried Wilhelm Leibniz Prize and Ernst Jung Prize for Medicine.

“I’m thrilled to be joining the accomplished team at BioTheryX by serving on the company’s SAB,” commented Dr. Schulman. “BioTheryX’s compelling and competitive platform creates a wealth of potential applications to degrade proteins with molecular glues, PHM based Proteolysis Targeting Chimeras, and monovalent degraders. I look forward to leveraging my expertise in this area and helping to advance BioTheryX to its next stages of growth.”

The backgrounds of the entire BioTheryX SAB can be found on the leadership page of the company’s website at https://biotheryx1.wpengine.com/about-us/#leadership.

About BioTheryX, Inc.

BioTheryX is a clinical-stage biopharmaceutical company focused on restoring protein homeostasis, including protein degradation and modulation, and multi-kinase inhibition to develop treatments intended to extend and improve the quality-of-life of patients with cancer and other diseases. Our principal technology platform centers on targeted protein degradation, PHM^® ‘molecular glues’, that enable the design of small molecules to regulate protein equilibrium. This technology is designed to utilize the body’s own protein disposal system to selectively degrade and remove disease-causing proteins. It has potential applicability for a broad range of diseases, including targets that have to date been considered ‘undruggable’, and BioTheryX is initially focused on treating oncology indications with high unmet need. For more information, please visit www.biotheryx.com and engage with us on LinkedIn.

Contact

Media and Investor Contact:
Amy Conrad, Juniper Point
(858) 366-3243
[email protected]

Last Updated on September 29, 2022 by biotheryx

SAN DIEGO, May 4, 2021 /PRNewswire/ —

BioTheryX, Inc., a clinical-stage company focused on degrading proteins to create life-saving medicines, today announced that the company will present virtually at the 2021 RBC Capital Markets Global Healthcare Conference on Thursday, May 20th, 2021 at 12:05 pm ET.

Rob Williamson, President and CEO, will present an overview on the company’s targeted protein degradation platform, its clinical stage oncology pipeline, and the management team will participate in 1x1s with investors.

About BioTheryX, Inc.

BioTheryX is a clinical-stage biopharmaceutical company focused on restoring protein homeostasis, including protein degradation and modulation, and multi-kinase inhibition to develop treatments intended to extend and improve the quality-of-life of patients with cancer and other diseases. Our principal technology platform centers on targeted protein degradation, PHM® ‘molecular glues’, that enable the design of small molecules to regulate protein equilibrium. This technology is designed to utilize the body’s own protein disposal system to selectively degrade and remove disease-causing proteins. It has potential applicability for a broad range of diseases, including targets that have to date been considered ‘undruggable’, and BioTheryX is initially focused on treating oncology indications with high unmet need. For more information, please visit www.biotheryx.com and engage with us on LinkedIn.

Contact

Media and Investor Contact:
Amy Conrad, Juniper Point
(858) 366-3243
[email protected]